A practical and chemoselective reduction of nitroarenes to anilines using activated iron

被引：129

作者：

Liu, YG ^{[1
]}

Lu, YS ^{[1
]}

Prashad, M ^{[1
]}

Repic, J ^{[1
]}

Blacklock, TJ ^{[1
]}

机构：

[1] Novartis Inst Biomed Res, Dept Chem & Analyt Dev, E Hanover, NJ 07936 USA

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2005年 / 347卷 / 2-3期

关键词：

anilines; chemoselectivity; iron; nitroarenes; reduction; zinc;

D O I：

10.1002/adsc.200404236

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Reduction of nitroarenes to anilines using activated iron generated by Fe/HCl or Zn/FeSO4 is described. A variety of functional groups such as alkyne, ketone, enone, nitrile, lactone, and aromatic halide are well tolerated under these conditions.

引用

页码：217 / 219

页数：3

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