New triterpene oligoglycosides from the Caribbean sponge Erylus formosus

被引：10

作者：

Antonov, Alexandr S. ^{[1
]}

Kalinovsky, Anatoly I. ^{[1
]}

Dmitrenok, Pavel S. ^{[1
]}

Kalinin, Vladimir I. ^{[1
]}

Stonik, Valentin A. ^{[1
]}

Mollo, Ernesto ^{[2
]}

Cimino, Guido ^{[2
]}

机构：

[1] Russian Acad Sci, Pacific Inst Bioorgan Chem, Far E Div, Vladivostok 690022, Russia

[2] Inst Chim Biomol CNR, I-80078 Naples, Italy

来源：

CARBOHYDRATE RESEARCH | 2011年 / 346卷 / 14期

基金：

俄罗斯基础研究基金会;

关键词：

Erylus formosus; Marine sponges; Erylosides; Triterpene glycosides; STEROID GLYCOSIDES; ERYLOSIDE; BIOSYNTHESIS; SPECTROSCOPY; SAPONIN; SUGARS;

D O I：

10.1016/j.carres.2011.07.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Seven new triterpene glycosides, erylosides R-1 (1). T-1 (3), T-2 (4), T-3 (5), T-4 (6), T-5 (7), and T-6 (8) along with the known formoside (2) were isolated from the sponge Erylus formosus collected along the Caribbean coast of Mexico. Glycoside 1 was determined as a trisaccharide, glycoside 2 as a tetrasaccharide while glycosides 3-8 were hexasaccharide. Their carbohydrate chains were unprecedented and have never been found in oligosaccharides from other biological sources, except Erylus spp. Three carbohydrate chains in the glycosides 3 and 6, 4 and 7, 5 and 8 correspondingly are new. The glycosides 1-5 have penasterol as aglycone while glycosides 6-8 proved to be glycoconjugates of 24-methylene-14-carboxy-lanost-8(9)-en-3 beta-ol. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：2182 / 2192

页数：11

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