Experimental and theoretical studies on the oxidative addition of palladium(0) to β-chlorovinamidinium salts

被引：8

作者：

Davies, IW

Wu, J

Marcoux, JF

Taylor, M

Hughes, D

Reider, PJ

Deeth, RJ

机构：

[1] Merck & Co Inc, Dept Proc Res, Rahway, NJ 07065 USA

[2] Univ Warwick, Inorgan Computat Chem Grp, Coventry CV4 7AL, W Midlands, England

来源：

TETRAHEDRON | 2001年 / 57卷 / 24期

关键词：

D O I：

10.1016/S0040-4020(01)00350-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Boronic acids, esters and borinic anhydrides are partners in Suzuki-Miyaura cross-coupling reactions with a variety of beta -chlorovinamidinium salts to give the desired beta -arylvinamidinium salts in up to 88% yield. Reduction is a competing reaction pathway. DFT calculations on the intermediate palladium complex reveal that the Pd-C interaction is predominantly of a-symmetry and the metal based LUMO is mainly d(z2) in character. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：5061 / 5066

页数：6

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