Novel gene cassettes and integrons

被引：48

作者：

Peters, EDJ ^{[1
]}

Leverstein-van Hall, MA ^{[1
]}

Box, ATA ^{[1
]}

Verhoef, J ^{[1
]}

Fluit, AC ^{[1
]}

机构：

[1] Univ Utrecht, Med Ctr, Eijkman Winkler Inst, NL-3508 GA Utrecht, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 10期

关键词：

D O I：

10.1128/AAC.45.10.2961-2964.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An increase in multiresistant Enterobacteriaceae was observed at one of the departments of the University Medical Center Utrecht. Nine different integrons and 17 gene cassettes were found, including the new gene cassette aadA8. This cassette was highly related to aadA3 and aadA2. In addition, an unknown promoter sequence was found for two integrons.

引用

页码：2961 / 2964

页数：4

共 12 条

[1] Class 1 integrons, gene cassettes, mobility, and epidemiology [J].

Fluit, AC ;

Schmitz, FJ .

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1999, 18 (11) :761-770

[2]

Gonzalez G, 1998, FEMS MICROBIOL LETT, V161, P125

[3] MOBILE GENE CASSETTES AND INTEGRONS - CAPTURE AND SPREAD OF GENES BY SITE-SPECIFIC RECOMBINATION [J].

HALL, RM ;

COLLIS, CM .

MOLECULAR MICROBIOLOGY, 1995, 15 (04) :593-600

[4] Widespread occurrence of integrons causing multiple antibiotic resistance in bacteria [J].

Jones, ME ;

Peters, E ;

Weersink, AM ;

Fluit, A ;

Verhoef, J .

LANCET, 1997, 349 (9067) :1742-1743

[5] DIVERSITY AND RELATIVE STRENGTH OF TANDEM PROMOTERS FOR THE ANTIBIOTIC-RESISTANCE GENES OF SEVERAL INTEGRONS [J].

LEVESQUE, C ;

BRASSARD, S ;

LAPOINTE, J ;

ROY, PH .

GENE, 1994, 142 (01) :49-54

[6] PCR MAPPING OF INTEGRONS REVEALS SEVERAL NOVEL COMBINATIONS OF RESISTANCE GENES [J].

LEVESQUE, C ;

PICHE, L ;

LAROSE, C ;

ROY, PH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :185-191

[7] Class I integrons in Gram-negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compounds [J].

Martinez-Freijo, P ;

Fluit, AC ;

Schmitz, FJ ;

Grek, VSC ;

Verhoef, J ;

Jones, ME .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1998, 42 (06) :689-696

[8] The resistance and integrase genes of pACM1, a conjugative multiple-resistance plasmid, from Klebsiella oxytoca [J].

Preston, KE ;

Kacica, MA ;

Limberger, RJ ;

Archinal, WA ;

Venezia, RA .

PLASMID, 1997, 37 (02) :105-118

[9] Gene cassettes: A new class of mobile element [J].

Recchia, GD ;

Hall, RM .

MICROBIOLOGY-UK, 1995, 141 :3015-3027

[10] Molecular epidemiology of integron-associated antibiotic resistance genes in clinical isolates of enterobacteriaceae [J].

Sallen, B ;

Rajoharison, A ;

Desvarenne, S ;

Mabilat, C .

MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE, 1995, 1 (03) :195-202

← 1 2 →