Fluvoxamine attenuates panic induced by 35% CO2 challenge

被引：40

作者：

Pols, HJ

Hauzer, RC

Meijer, JA

Verburg, K

Griez, EJ

机构：

[1] Dept. of Psychiat. and Neuropsychol., Sect. of Clin. and Biol. Psychiatry, State University of Limburg, Maastricht

[2] Dept. of Psychiat. and Neuropsychol., Sect. of Clin. and Biol. Psychiatry, State University of Limburg, 6200 MD Maastricht

来源：

JOURNAL OF CLINICAL PSYCHIATRY | 1996年 / 57卷 / 11期

关键词：

D O I：

10.4088/JCP.v57n1107

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Background: The authors investigated whether 6 weeks of treatment with fluvoxamine would decrease the anxiogenic response to the 35% CO2 challenge in 11 patients with DSM-III-R panic disorder with agoraphobia. Method: The patients underwent a 35% CO, challenge at baseline and again after 6 weeks of fluvoxamine treatment. Results: The anxiogenic effect of CO, was significantly (p < .05) reduced during fluvoxamine treatment. Conclusion: The results suggest a relationship between the anxiogenic effect of CO2 and the therapeutic effect of fluvoxamine.

引用

页码：539 / 542

页数：5