A new synthesis of alpha-tetralones.

被引:78
作者
Liard, A
QuicletSire, B
Saicic, RN
Zard, SZ
机构
[1] ECOLE POLYTECH,SYNTH ORGAN LAB,CNRS,F-91128 PALAISEAU,FRANCE
[2] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE
关键词
D O I
10.1016/S0040-4039(97)00184-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
alpha-tetralones 8a-j can be prepared by radical cyclisation, in the presence of stoichiometric amounts of lauroyl peroxide, of xanthates 5a-j obtained by an intermolecular addition of substituted S-phenacyl xanthates 4a-c to various olefins. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:1759 / 1762
页数:4
相关论文
共 29 条
[21]   OXIDATIVE CYCLIZATION OF DELTA,EPSILON-UNSATURATED AND EPSILON,ZETA-UNSATURATED ENOL SILYL ETHERS [J].
SNIDER, BB ;
KWON, T .
JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (16) :4786-4788
[22]   Stereocontrolled synthesis of (+/-)-12a-deoxytetracycline [J].
Stork, G ;
LaClair, JJ ;
Spargo, P ;
Nargund, RP ;
Totah, N .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (22) :5304-5305
[23]  
TAMCHOMPOO B, 1986, SYNTHESIS-STUTTGART, P785
[24]   Tributylstannyl 4-tributylstannylbut-3-enoate: A useful C-4 homologating agent. Application to the synthesis of aryl iodolactones [J].
Thibonnet, J ;
Abarbri, M ;
Parrain, JL ;
Duchene, A .
TETRAHEDRON LETTERS, 1996, 37 (42) :7507-7510
[25]   Tetrahydronaphthalenes: Influence of heterocyclic substituents on inhibition of steroidogenic enzymes P450 arom and P450 17 [J].
Wachter, GA ;
Hartmann, RW ;
Sergejew, T ;
Grun, GL ;
Ledergerber, D .
JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (04) :834-841
[26]   SIMPLE ROUTE TO SUBSTITUTED TETRALONES [J].
YANG, FZ ;
TROST, MK ;
FRISTAD, WE .
TETRAHEDRON LETTERS, 1987, 28 (14) :1493-1496
[27]  
ZARD SZ, 1993, ACTUAL CHIM, P10
[28]  
ZARD SZ, 1994, TETRAHEDRON LETT, V35, P1719
[29]  
ZHAO DY, 1994, SYNTHESIS-STUTTGART, P915