Biodegradable Multi-liposomal Containers

被引：10

作者：

Efimova, A. A. ^{[1
]}

Sybachin, A. V. ^{[1
]}

Chvalun, S. N. ^{[2
]}

Kulebyakina, A. I. ^{[2
]}

Kozlova, E. V. ^{[2
]}

Yaroslavov, A. A. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Chem, Moscow 119991, Russia

[2] Kurchatov Inst, Natl Res Ctr, Moscow 123182, Russia

来源：

POLYMER SCIENCE SERIES B | 2015年 / 57卷 / 02期

基金：

俄罗斯科学基金会;

关键词：

COMPLEXES; DELIVERY; DNA;

D O I：

10.1134/S1560090415020050

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

The method of preparing biodegradable multi-liposomal containers via modification of anionic liposomes with a cationic polymer and subsequent adsorption of the obtained liposome-polymer cationic complex on the surfaces of negatively charged polylactide micelles with grafted polyoxyethylene chains is described. Liposomes preserve their integrity in a ternary micelle-polycation-liposome complex, a circumstance that allows the complex to be used as a multi-liposomal container for encapsulation of bioactive compounds.

引用

页码：140 / 144

页数：5

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