Cross-coupling reactions of hypervalent siloxane derivatives: An alternative to Stille and Suzuki couplings

被引：179

作者：

Mowery, ME ^{[1
]}

DeShong, P ^{[1
]}

机构：

[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 05期

关键词：

D O I：

10.1021/jo982463h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed cross-coupling of phenyl, vinyl, and allyl siloxane derivatives proceeded in good to excellent yield with aryl iodides, electron-deficient aryl bromides, and allylic benzoates. Methyl and 2,2,2-trifluoroethyl siloxane derivatives can be employed in the coupling reaction. Electron-donating and -withdrawing groups are tolerated on the aryl halide without affecting the coupling. The scope and limitations of this alternative to Stille and Suzuki couplings is outlined.

引用

页码：1684 / 1688

页数：5

共 54 条

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