Facile and green production of aqueous graphene dispersions for biomedical applications

被引:117
作者
Ahadian, Samad [1 ]
Estili, Mehdi [2 ]
Surya, Velappa Jayaraman [3 ]
Ramon-Azcon, Javier [1 ]
Liang, Xiaobin [1 ]
Shiku, Hitoshi [4 ]
Ramalingam, Murugan [1 ,5 ,6 ]
Matsue, Tomokazu [1 ,4 ]
Sakka, Yoshio [7 ]
Bae, Hojae [8 ]
Nakajima, Ken [1 ]
Kawazoe, Yoshiyuki [3 ,13 ]
Khademhosseini, Ali [1 ,8 ,9 ,10 ,11 ,12 ]
机构
[1] Tohoku Univ, WPI Adv Inst Mat Res, Sendai, Miyagi 9808577, Japan
[2] Natl Inst Mat Sci, ICYS, Tsukuba, Ibaraki 3050047, Japan
[3] Tohoku Univ, New Ind Creat Hatchery Ctr, Sendai, Miyagi 9808579, Japan
[4] Tohoku Univ, Grad Sch Environm Studies, Sendai, Miyagi 9808579, Japan
[5] Ctr Stem Cell Res, Vellore 632002, Tamil Nadu, India
[6] Univ Strasbourg, Fac Chirurg Dent, INSERM, U977, F-67085 Strasbourg, France
[7] Natl Inst Mat Sci, Mat Proc Unit, Tsukuba, Ibaraki 3050047, Japan
[8] Konkuk Univ, Dept Bioind Technol, Coll Anim Biosci & Technol, Seoul 143701, South Korea
[9] Harvard Univ, Brigham & Womens Hosp, Biomat Innovat Res Ctr, Dept Med,Med Sch, Cambridge, MA 02139 USA
[10] MIT, Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA
[11] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02115 USA
[12] King Abdulaziz Univ, Dept Phys, Fac Sci, Jeddah 21569, Saudi Arabia
[13] Russian Acad Sci, Inst Thermophys, Siberian Branch, Novosibirsk 630090, Russia
关键词
CELLULAR INTERFACES; GRAPHITE; OXIDE; FILMS; DIFFERENTIATION; EXFOLIATION; TRANSISTORS; NANOSHEETS; HYDROGELS; DESIGN;
D O I
10.1039/c4nr07569b
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
We proposed a facile, low cost, and green approach to produce stable aqueous graphene dispersions from graphite by sonication in aqueous bovine serum albumin (BSA) solution for biomedical applications. The production of high-quality graphene was confirmed using microscopy images, Raman spectroscopy, UV-vis spectroscopy, and XPS. In addition, ab initio calculations revealed molecular interactions between graphene and BSA. The processability of aqueous graphene dispersions was demonstrated by fabricating conductive and mechanically robust hydrogel-graphene materials.
引用
收藏
页码:6436 / 6443
页数:8
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