The use of neoral in rheumatoid arthritis

被引：12

作者：

Cranney, A ^{[1
]}

Tugwell, P ^{[1
]}

机构：

[1] Univ Ottawa, Dept Med, Ottawa, ON K1H 8L6, Canada

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 1998年 / 24卷 / 03期

关键词：

D O I：

10.1016/S0889-857X(05)70021-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neoral (a microemulsion-based formulation) is an immunomodulator that possesses a more predictable and improved absorption than the conventional oral formulation (Sandimmun). The increased bioavailability of Neoral could result in improved efficacy. The pharmacokinetics of cyclosporin and efficacy of cyclosporin in rheumatoid arthritis are reviewed in this article. Current guidelines for the use of Neoral in the treatment of rheumatoid arthritis patients are outlined.

引用

页码：479 / +

页数：11

共 36 条

[1] A RANDOMIZED DOUBLE-BLIND TRIAL OF CYCLOSPORINE AND AZATHIOPRINE IN REFRACTORY RHEUMATOID-ARTHRITIS
AHERN, MJ
HARRISON, W
HOLLINGSWORTH, P
BRADLEY, J
LAING, B
BAYLISS, C
[J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1991, 21 (06): : 844 - 849
[2] ARELLANO F, 1994, BR J RHEUMATOL S1, V33, P72
[3] ASSAN R, 1994, CLIN NEPHROL, V41, P41
[4] BENSEN W, 1994, J RHEUMATOL, V21, P2034
[5] BERG KJ, 1989, CLIN NEPHROL, V31, P232
[6] RENAL FINDINGS IN RHEUMATOID-ARTHRITIS - CLINICAL ASPECTS OF 132 NECROPSIES
BOERS, M
CROONEN, AM
DIJKMANS, BAC
BREEDVELD, FC
EULDERINK, F
CATS, A
WEENING, JJ
[J]. ANNALS OF THE RHEUMATIC DISEASES, 1987, 46 (09) : 658 - 663
[7] BOREL J, 1997, IMMUNOLOGY, V32, P1017
[8] COCKBURN ITR, 1989, J AUTOIMMUN, V27, P23
[9] CYCLOSPORINE IN RHEUMATOID-ARTHRITIS
DIJKMANS, BAC
VANRIJTHOVEN, AWAM
THE, HSG
BOERS, M
CATS, A
[J]. SEMINARS IN ARTHRITIS AND RHEUMATISM, 1992, 22 (01) : 30 - 36
[10] DOUGADOS M, 1988, ANN RHEUM DIS, V109, P863

← 1 2 3 4 →