The use of neoral in rheumatoid arthritis

被引：12

作者：

Cranney, A ^{[1
]}

Tugwell, P ^{[1
]}

机构：

[1] Univ Ottawa, Dept Med, Ottawa, ON K1H 8L6, Canada

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 1998年 / 24卷 / 03期

关键词：

D O I：

10.1016/S0889-857X(05)70021-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neoral (a microemulsion-based formulation) is an immunomodulator that possesses a more predictable and improved absorption than the conventional oral formulation (Sandimmun). The increased bioavailability of Neoral could result in improved efficacy. The pharmacokinetics of cyclosporin and efficacy of cyclosporin in rheumatoid arthritis are reviewed in this article. Current guidelines for the use of Neoral in the treatment of rheumatoid arthritis patients are outlined.

引用

页码：479 / +

页数：11

共 36 条

[31] VANRIJTHOVEN AWAM, 1991, J RHEUMATOL, V18, P815
[32] WELLS G, 1993, BR J RHEUMATOL S, V32, P57
[33] THE MECHANISM OF ACTION OF FK-506 AND CYCLOSPORINE-A
WIEDERRECHT, G
LAM, E
HUNG, S
MARTIN, M
SIGAL, N
[J]. IMMUNOSUPPRESSIVE AND ANTIINFLAMMATORY DRUGS, 1993, 696 : 9 - 19
[34] WOODSWORTH BP, 1989, P NATL ACAD SIC US, V86, P1049
[35] Yocum DE, 1996, BRIT J RHEUMATOL, V35, P19
[36] CYCLOSPORIN-A IN SEVERE, TREATMENT-REFRACTORY RHEUMATOID-ARTHRITIS - A RANDOMIZED STUDY
YOCUM, DE
KLIPPEL, JH
WILDER, RL
GERBER, NL
AUSTIN, HA
WAHL, SM
LESKO, L
MINOR, JR
PREUSS, HG
YARBORO, C
BERKEBILE, C
DOUGHERTY, S
[J]. ANNALS OF INTERNAL MEDICINE, 1988, 109 (11) : 863 - 869

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