Regulation of hematopoiesis by chemokine family members

被引:80
作者
Broxmeyer, HE
机构
[1] Indiana Univ, Sch Med, Walther Oncol Ctr, Indianapolis, IN 46202 USA
[2] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
[3] Walther Canc Inst, Indianapolis, IN USA
关键词
chemokines; stem/progenitor cells; proliferation; survival; migration/homing;
D O I
10.1007/BF02982544
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells. (C) 2001 The Japanese Society of Hematology.
引用
收藏
页码:9 / 17
页数:9
相关论文
共 89 条
  • [1] The chemokine SDF-1 is a chemoattractant for human CD34(+) hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34(+) progenitors to peripheral blood
    Aiuti, A
    Webb, IJ
    Bleul, C
    Springer, T
    GutierrezRamos, JC
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (01) : 111 - 120
  • [2] INTERFERON-INDUCIBLE PROTEIN-10 AND MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA INHIBIT GROWTH-FACTOR STIMULATION OF RAF-1 KINASE-ACTIVITY AND PROTEIN-SYNTHESIS IN A HUMAN GROWTH FACTOR-DEPENDENT HEMATOPOIETIC-CELL LINE
    ARONICA, SM
    MANTEL, C
    GONIN, R
    MARSHALL, MS
    SARRIS, A
    COOPER, S
    HAGUE, N
    ZHANG, XF
    BROXMEYER, HE
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (37) : 21998 - 22007
  • [3] Human chemokines: An update
    Baggiolini, M
    Dewald, B
    Moser, B
    [J]. ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 : 675 - 705
  • [4] Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs
    Blalock, WL
    Weinstein-Oppenheimer, C
    Chang, F
    Hoyle, PE
    Wang, XY
    Algate, PA
    Franklin, RA
    Oberhaus, SM
    Steelman, LS
    McCubrey, JA
    [J]. LEUKEMIA, 1999, 13 (08) : 1109 - 1166
  • [5] A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
    Bleul, CC
    Fuhlbrigge, RC
    Casasnovas, JM
    Aiuti, A
    Springer, TA
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (03) : 1101 - 1109
  • [6] Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
    Boring, L
    Gosling, J
    Chensue, SW
    Kunkel, SL
    Farese, RV
    Broxmeyer, HE
    Charo, IF
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (10) : 2552 - 2561
  • [7] Stem cell factor and hematopoiesis
    Broudy, VC
    [J]. BLOOD, 1997, 90 (04) : 1345 - 1364
  • [8] BROXMEYER HE, 1990, BLOOD, V76, P1110
  • [9] BROXMEYER HE, 1992, AM J PEDIAT HEMATOL, V14, P22
  • [10] BROXMEYER HE, 1991, CANCER CELL-MON REV, V3, P480