Regulation of hematopoiesis by chemokine family members

被引:80
作者
Broxmeyer, HE
机构
[1] Indiana Univ, Sch Med, Walther Oncol Ctr, Indianapolis, IN 46202 USA
[2] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA
[3] Walther Canc Inst, Indianapolis, IN USA
关键词
chemokines; stem/progenitor cells; proliferation; survival; migration/homing;
D O I
10.1007/BF02982544
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells. (C) 2001 The Japanese Society of Hematology.
引用
收藏
页码:9 / 17
页数:9
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