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Brain natriuretic peptide in the management of heart failure - The versatile neurohormone

被引：62
作者：
de Denus, S
Williamson, DR
机构：
[1] Univ Montreal, Hop Sacre Coeur, Fac Pharm, Montreal, PQ H4J 1C5, Canada
[2] Univ Sci Philadelphia, Coll Pharm, Philadelphia, PA USA
来源：
CHEST | 2004年 / 125卷 / 02期
关键词：
brain natriuretic peptide; congestive heart failure; nesiritide;
D O I：
10.1378/chest.125.2.652
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Brain natriuretic peptide (BNP), also called B-type natriuretic peptide, is a member of a family of structurally related hormones, the natriuretic peptides. Current data suggest that measurement of BNP plasma concentrations is a useful tool in the diagnosis of acute heart failure in patients presenting to an emergency department with acute dyspnea. Furthermore, BNP constitutes a promising new marker of prognosis after an acute coronary syndrome episode and in patients with chronic heart failure. Nesiritide, the human recombinant form of BNP, is a new vasodilator used in the treatment of acute heart failure that has several potential advantages over current drug therapy.
引用
收藏
页码：652 / 668
页数：17
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