Immunomodulation: a new role for statins?

被引：93

作者：

Palinski, W ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA

来源：

NATURE MEDICINE | 2000年 / 6卷 / 12期

关键词：

D O I：

10.1038/82107

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Statins reduce the expression of the class II major histocompatibility complex (MHCII) by arterial cells, leading to a decreased T-cell response. This indicates that statins may be useful in treating graft atherosclerosis and other chronic inflammatory conditions.

引用

页码：1311 / 1312

页数：2

共 12 条

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