Immunomodulation: a new role for statins?

被引:93
作者
Palinski, W [1 ]
机构
[1] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
关键词
D O I
10.1038/82107
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Statins reduce the expression of the class II major histocompatibility complex (MHCII) by arterial cells, leading to a decreased T-cell response. This indicates that statins may be useful in treating graft atherosclerosis and other chronic inflammatory conditions.
引用
收藏
页码:1311 / 1312
页数:2
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