Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3+2] dipolar cycloaddition reaction

被引：195

作者：

Dirks, AJT ^{[1
]}

van Berkel, SS ^{[1
]}

Hatzakis, NS ^{[1
]}

Opsteen, JA ^{[1
]}

van Delft, FL ^{[1
]}

Cornelissen, JJLM ^{[1
]}

Rowan, AE ^{[1
]}

van Hest, JCM ^{[1
]}

Rutjes, FPJT ^{[1
]}

Nolte, RJM ^{[1
]}

机构：

[1] Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 ED Nijmegen, Netherlands

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 33期

关键词：

D O I：

10.1039/b508428h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biohybrid amphiphiles have been prepared from terminal azide functionalised polystyrene and an alkyne functionalised peptide or protein via a Cu(I) catalysed Huisgen [3 + 2] dipolar cycloaddition reaction.

引用

页码：4172 / 4174

页数：3

共 29 条

[1] Peptide-polymer bioconjugates:: hybrid block copolymers generated via living radical polymerizations from resin-supported peptides
Becker, ML
Liu, JQ
Wooley, KL
[J]. CHEMICAL COMMUNICATIONS, 2003, (02) : 180 - 181
[2] Boerakker MJ, 2002, ANGEW CHEM INT EDIT, V41, P4239, DOI 10.1002/1521-3773(20021115)41:22<4239::AID-ANIE4239>3.0.CO
[3] 2-E
[4] Streptavidin as a macroinitiator for polymerization: In situ protein-polymer conjugate formation
Bontempo, D
Maynard, HD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (18) : 6508 - 6509
[5] Cysteine-reactive polymers synthesized by atom transfer radical polymerization for conjugation to proteins
Bontempo, D
Heredia, KL
Fish, BA
Maynard, HD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (47) : 15372 - 15373
[6] CARTER DC, 1994, ADV PROTEIN CHEM, V45, P153
[7] CHECOT F, 2002, ANGEW CHEM INT EDIT, V41, P1509
[8] Site-specific PEGylation of proteins containing unnatural amino acids
Deiters, A
Cropp, TA
Summerer, D
Mukherji, M
Schultz, PG
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (23) : 5743 - 5745
[9] Click chemistry in materials synthesis.: 1.: Adhesive polymers from copper-catalyzed azide-alkyne cycloaddition
Díaz, DD
Punna, S
Holzer, P
Mcpherson, AK
Sharpless, KB
Fokin, VV
Finn, MG
[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2004, 42 (17) : 4392 - 4403
[10] Polymer vesicles
Discher, DE
Eisenberg, A
[J]. SCIENCE, 2002, 297 (5583) : 967 - 973

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