Quantitative analysis of random ameboid motion

被引：57

作者：

Boedeker, H. U. ^{[1
]}

Beta, C. ^{[2
,3
]}

Frank, T. D. ^{[4
]}

Bodenschatz, E. ^{[3
]}

机构：

[1] WWU Munster, Inst Angew Phys, D-48149 Munster, Germany

[2] Univ Potsdam, Inst Phys & Astron, D-14476 Potsdam, Germany

[3] Max Planck Inst Dynam & Self Org, D-37077 Gottingen, Germany

[4] Univ Connecticut, Ctr Ecol Study Percept & Act, Storrs, CT 06269 USA

来源：

EPL | 2010年 / 90卷 / 02期

关键词：

CELL MOTILITY; CHEMOTAXIS; DIFFUSION; MODEL;

D O I：

10.1209/0295-5075/90/28005

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We quantify random migration of the social ameba Dictyostelium discoideum. We demonstrate that the statistics of cell motion can be described by an underlying Langevin-type stochastic differential equation. An analytic expression for the velocity distribution function is derived. The separation into deterministic and stochastic parts of the movement shows that the cells undergo a damped motion with multiplicative noise. Both contributions to the dynamics display a distinct response to external physiological stimuli. The deterministic component depends on the developmental state and ambient levels of signaling substances, while the stochastic part does not. Copyright (C) EPLA, 2010

引用

页数：5

共 31 条

[1] Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions [J].

Andrew, Natalie ;

Insall, Robert H. .

NATURE CELL BIOLOGY, 2007, 9 (02) :193-U91

[2]

Berg HC., 2003, E. coli in motion

[3] Noise-covered drift bifurcation of dissipative solitons in a planar gas-discharge system -: art. no. 056220 [J].

Bödeker, HU ;

Röttger, MC ;

Liehr, AW ;

Frank, TD ;

Friedrich, R ;

Purwins, HG .

PHYSICAL REVIEW E, 2003, 67 (05) :12

[4] Exponential distribution of locomotion activity in cell cultures [J].

Czirok, A ;

Schlett, K ;

Madarasz, E ;

Vicsek, T .

PHYSICAL REVIEW LETTERS, 1998, 81 (14) :3038-3041

[5] Anomalous dynamics of cell migration [J].

Dieterich, Peter ;

Klages, Rainer ;

Preuss, Roland ;

Schwab, Albrecht .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (02) :459-463

[6] Description of a turbulent cascade by a Fokker-Planck equation [J].

Friedrich, R ;

Peinke, J .

PHYSICAL REVIEW LETTERS, 1997, 78 (05) :863-866

[7] The Brownian motion with consideration of the longevity of the direction of movement. [J].

Furth, R .

ZEITSCHRIFT FUR PHYSIK, 1920, 2 :244-256

[8]

GEISEL T, 1985, PHYS REV LETT, V54, P616, DOI 10.1103/PhysRevLett.54.616

[9] Analysis of time series from stochastic processes [J].

Gradisek, J ;

Siegert, S ;

Friedrich, R ;

Grabec, I .

PHYSICAL REVIEW E, 2000, 62 (03) :3146-3155

[10] STOCHASTIC-PROCESSES - TIME EVOLUTION, SYMMETRIES AND LINEAR RESPONSE [J].

HANGGI, P ;

THOMAS, H .

PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS, 1982, 88 (04) :207-319

← 1 2 3 4 →