Thymoma

被引:101
作者
Müller-Hermelink, HK [1 ]
Marx, A [1 ]
机构
[1] Univ Wurzburg, Dept Pathol, D-97080 Wurzburg, Germany
关键词
D O I
10.1097/00001622-200009000-00007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Thymomas are fascinating tumors because of their multifaceted clinical presentation, including an unrivaled frequency of associated paraneoplastic autoimmune diseases and an astounding histologic heterogeneity. Thus, thymomas challenge the clinician, pathologist, and immunologist alike with complex diagnostic and therapeutic problems in almost all fields of medicine, radiology, nuclear medicine, surgery, radiooncology, and pathology. This review highlights recent progress in these fields, including the new World Health Organization's classification of thymomas, and reports on the beginning discovery of the genetic basis of thymoma oncogenesis and the cellular and molecular immunopathology of thymoma-associated paraneoplastic autoimmunity. Curr Opin Oncol 2000, 12:426-433 (C) 2000 Lippincott Williams & Wilkins, Inc.
引用
收藏
页码:426 / 433
页数:8
相关论文
共 78 条
[1]   Dermatomyositis associated with invasive thymoma [J].
Ago, T ;
Nakamura, M ;
Iwata, I ;
Murai, H ;
Okuma, K ;
Tsuru, T ;
Kaji, Y ;
Hayashida, K ;
Niho, Y .
INTERNAL MEDICINE, 1999, 38 (02) :155-159
[2]  
BERNATZ PE, 1961, J THORAC CARDIOV SUR, V42, P424
[3]   Primary chemotherapy with adriamycin, cisplatin, vincristine and cyclophosphamide in locally advanced thymomas: a single institution experience [J].
Berruti, A ;
Borasio, P ;
Gerbino, A ;
Gorzegno, G ;
Moschini, T ;
Tampellini, M ;
Ardissone, F ;
Brizzi, MP ;
Dolcetti, A ;
Dogliotti, L .
BRITISH JOURNAL OF CANCER, 1999, 81 (05) :841-845
[4]   A minimal level of MHC class II expression is sufficient to abrogate autoreactivity [J].
de Bont, ESJM ;
Reilly, CR ;
Lo, D ;
Glimcher, LH ;
Laufer, TM .
INTERNATIONAL IMMUNOLOGY, 1999, 11 (08) :1295-1305
[5]   Multiple paraneoplastic diseases associated with thymoma [J].
Evoli, A ;
Lo Monaco, M ;
Marra, R ;
Lino, MM ;
Batocchi, AP ;
Tonali, PA .
NEUROMUSCULAR DISORDERS, 1999, 9 (08) :601-603
[6]   Thymoma and hypogammaglobulinemia, Good's syndrome: a case report and literature review. [J].
Granel, B ;
Gayet, S ;
Christides, C ;
Serratrice, J ;
Rey, J ;
Disdier, P ;
Weiller, PJ .
REVUE DE MEDECINE INTERNE, 1999, 20 (04) :347-349
[7]  
Gu FX, 1999, CUTIS, V64, P179
[8]  
Harris NL, 1999, AM J CLIN PATHOL, V112, P299
[9]   Antibodies to ion-channel proteins in thymoma with myasthenia, neuromyotonia, and peripheral neuropathy [J].
Heidenreich, F ;
Vincent, A .
NEUROLOGY, 1998, 50 (05) :1483-1485
[10]  
Hejna M, 1999, CANCER-AM CANCER SOC, V85, P1871, DOI 10.1002/(SICI)1097-0142(19990501)85:9<1871::AID-CNCR1>3.0.CO