Synergistic antibacterial activity between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts

被引：201

作者：

Al-Bayati, Firas A. ^{[1
]}

机构：

[1] Univ Mosul, Coll Educ, Dept Biol, Mosul, Iraq

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2008年 / 116卷 / 03期

关键词：

synergistic antibacterial activity; essential oils; methanol extract; Thymus vulgaris; Pimpinella anisum;

D O I：

10.1016/j.jep.2007.12.003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Essential oils (EOs) and methanol extracts obtained from aerial parts of Thymus vulgaris and Pimpinella anisum seeds were evaluated for their single and combined antibacterial activities against nine Gram-positive and Gram-negative pathogenic bacteria: Staphylococcus aureus, Bacillus cereus, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Salmonella typhi, Salmonella typhimurium, Klebsiella pneumoniae and Pseudomonas aeruginosa. The essential oils and methanol extracts revealed promising antibacterial activities against most pathogens using broth microdilution method. Maximum activity of Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts (MIC 15.6 and 62.5 mu g/ml) were observed against Staphylococcus aureus, Bacillus cereus and Proteus vulgaris. Combinations of essential oils and methanol extracts showed an additive action against most tested pathogens especially Pseudomonas aeruginosa. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：403 / 406

页数：4

共 34 条

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