Bilirubin-induced neurological damage

被引:9
作者
Gazzin, Silvia [1 ]
Tiribelli, Claudio [1 ,2 ]
机构
[1] Univ Trieste, Italian Liver Fdn, Ctr Liver Dis, I-34127 Trieste, Italy
[2] Univ Trieste, Dept Med Sci, I-34127 Trieste, Italy
关键词
jaundice; early discharge neurological damage; KERNICTERUS; NEWBORNS;
D O I
10.3109/14767058.2011.607590
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
The incidence of the neurological damage of due to severe neonatal jaundice is increasing mainly due to early discharge from the hospital. However the molecular mechanisms at the basis of the neurological damage are still largely unknown. We here summarize what is known and what is not yet known on how bilirubin may cause cellular damage to selective regions of the brain. This may hopefully help to develop diagnostic and therapeutic strategies for a more effective handling of this invalidating condition.
引用
收藏
页码:154 / 155
页数:2
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