Circadian rhythm photic phase shifts are not altered by histamine receptor antagonists

被引：11

作者：

Eaton, SJ ^{[1
]}

Eoh, S ^{[1
]}

Meyer, J ^{[1
]}

Hoque, S ^{[1
]}

Harrington, ME ^{[1
]}

机构：

[1] SMITH COLL,DEPT PSYCHOL,NORTHAMPTON,MA 01063

来源：

BRAIN RESEARCH BULLETIN | 1996年 / 41卷 / 04期

关键词：

cimetidine; circadian; histamine; mepyramine; thioperamide; zolantidine;

D O I：

10.1016/S0361-9230(96)00179-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Histamine may play a role in synchronizing endogenous circadian rhythms with exogenous photic cues. Direct application of histamine to the suprachiasmatic nucleus, the site of the mammalian circadian pacemaker, phase shifts the circadian rhythm in neural activity [7], Intraventricular injections of histamine also phase shift circadian rhythms [14]. The magnitude and direction of the phase shifting effects of histamine depend on circadian phase in a manner similar to light [7,14]. Depletion of brain histamine levels by inhibition of histamine synthesis reduces phase shifts to light [10]. Copyright (C) 1996 Elsevier Science Inc.

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收藏

页码：227 / 229

页数：3

相关论文

共 23 条

[1] HIGHLY POTENT AND SELECTIVE LIGANDS FOR HISTAMINE RECEPTORS-H-3 [J].

ARRANG, JM ;

GARBARG, M ;

LANCELOT, JC ;

LECOMTE, JM ;

POLLARD, H ;

ROBBA, M ;

SCHUNACK, W ;

SCHWARTZ, JC .

NATURE, 1987, 327 (6118) :117-123

[2] ENHANCEMENT BY HISTAMINE OF NMDA-MEDIATED SYNAPTIC TRANSMISSION IN THE HIPPOCAMPUS [J].

BEKKERS, JM .

SCIENCE, 1993, 261 (5117) :104-106

[3] CIMETIDINE - NON-THIOUREA H2-RECEPTOR ANTAGONIST [J].

BRIMBLECOMBE, RW ;

DUNCAN, WAM ;

DURANT, GJ ;

EMMETT, JC ;

GANELLIN, CR ;

PARSONS, ME .

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 1975, 3 (02) :86-92

[4] EFFECT OF HISTAMINE AND ANTAGONISTS ON ELECTRICAL-RESISTANCE ACROSS THE BLOOD-BRAIN-BARRIER IN RAT BRAIN-SURFACE MICROVESSELS [J].

BUTT, AM ;

JONES, HC .

BRAIN RESEARCH, 1992, 569 (01) :100-105

[5] HISTAMINE H-3 RECEPTORS MODULATE THE RELEASE OF [H-3] ACETYLCHOLINE FROM SLICES OF RAT ENTORHINAL CORTEX - EVIDENCE FOR THE POSSIBLE EXISTENCE OF H-3 RECEPTOR SUBTYPES [J].

CLAPHAM, J ;

KILPATRICK, GJ .

BRITISH JOURNAL OF PHARMACOLOGY, 1992, 107 (04) :919-923

[6] NMDA AS WELL AS NON-NMDA RECEPTOR ANTAGONISTS CAN PREVENT THE PHASE-SHIFTING EFFECTS OF LIGHT ON THE CIRCADIAN SYSTEM OF THE GOLDEN-HAMSTER [J].

COLWELL, CS ;

MENAKER, M .

JOURNAL OF BIOLOGICAL RHYTHMS, 1992, 7 (02) :125-136

[7] HISTAMINE PHASE-SHIFTS THE CIRCADIAN CLOCK IN A MANNER SIMILAR TO LIGHT [J].

COTE, NK ;

HARRINGTON, ME .

BRAIN RESEARCH, 1993, 613 (01) :149-151

[8] FUNCTIONAL-ANALYSIS OF CIRCADIAN PACEMAKERS IN NOCTURNAL RODENTS .2. VARIABILITY OF PHASE RESPONSE CURVES [J].

DAAN, S ;

PITTENDRIGH, CS .

JOURNAL OF COMPARATIVE PHYSIOLOGY, 1976, 106 (03) :253-266

[9]

DOI T, 1994, BRAIN RES, V641, P311, DOI 10.1016/0006-8993(94)90160-0

[10] HISTAMINE SYNTHESIS INHIBITION REDUCES LIGHT-INDUCED PHASE-SHIFTS OF CIRCADIAN-RHYTHMS [J].

EATON, SJ ;

COTE, NK ;

HARRINGTON, ME .

BRAIN RESEARCH, 1995, 695 (02) :227-230