Intron size and exon evolution in Drosophila

被引：93

作者：

Marais, G ^{[1
]}

Nouvellet, P ^{[1
]}

Keightley, PD ^{[1
]}

Charlesworth, B ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Biol Sci, Inst Evolutionary Biol, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

GENETICS | 2005年 / 170卷 / 01期

关键词：

D O I：

10.1534/genetics.104.037333

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We have found a negative correlation between evolutionary rate at the protein level (as measured by d(N)) and intron size in Drosophila. Although such a relation is expected if introns reduce Hill-Robertson interference within genes, it seems more likely to be explained by the higher abundance of cis-regulatory elements in introns (especially first introns) in genes under strong selective constraints.

引用

页码：481 / 485

页数：5

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