Vinylalumination of fluoro-carbonyl compounds

被引：33

作者：

Ramachandran, PV ^{[1
]}

Reddy, MVR ^{[1
]}

Rudd, MT ^{[1
]}

de Alaniz, JR ^{[1
]}

机构：

[1] Purdue Univ, HC Brown & RB Wetherill Labs Chem, W Lafayette, IN 47907 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(98)01974-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ethyl acrylate and acrylonitrile fail to undergo efficient Baylis-Hillman reaction with fluoral, but provide good yields of products with pentafluorobenzaldehyde. Alternately, unsubstituted and beta-substituted [alpha- (ethoxycarbonyl)vinyl]aluminum react with perfluoroalkyl and -aryl aldehydes and ketones to provide the alpha-hydroxyalkenylated fluoroorganic compounds in good to excellent yields. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8791 / 8794

页数：4