Free-living pathogens: Life-history constraints and strain competition

被引：59

作者：

Caraco, Thomas ^{[1
]}

Wang, Ing-Nang ^{[1
]}

机构：

[1] SUNY Albany, Dept Biol Sci, Albany, NY 12222 USA

来源：

JOURNAL OF THEORETICAL BIOLOGY | 2008年 / 250卷 / 03期

关键词：

host preemption; infectious-particle longevity; pathogen evolution; virulence; trade-offs;

D O I：

10.1016/j.jtbi.2007.10.029

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Many pathogen life histories include a free-living stage, often with anatomical and physiological adaptations promoting persistence outside of host tissues. More durable particles presumably require that the pathogen metabolize more resources per particle. Therefore, we hypothesize functional dependencies, pleiotropic constraints, between the rate at which free-living particles decay outside of host tissues and other pathogen traits, including virulence, the probability of infecting a host upon contact, and pathogen reproduction within host tissues. Assuming that pathogen strains compete for hosts preemptively, we find patterns in trait dependencies predicting whether or not strain competition favors a highly persistent free-living stage. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：569 / 579

页数：11

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