VIM-12, a novel plasmid-mediated metallo-β-lactamase from Klebsiella pneumoniae that resembles a VIM-1/VIM-2 hybrid

被引：37

作者：

Pournaras, S

Ikonomidis, A

Tzouvelekis, LS

Tokatlidou, D

Spanakis, N

Maniatis, AN

Legakis, NJ

Tsakris, A

机构：

[1] Univ Thessaloniki, Sch Med, Dept Microbiol, Larisa, Greece

[2] Univ Athens, Sch Med, Dept Microbiol, GR-10679 Athens, Greece

[3] Hippokrateion Hosp, Dept Microbiol, Thessaloniki, Greece

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 12期

关键词：

D O I：

10.1128/AAC.49.12.5153-5156.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A transferable plasmid from Klebsiella pneumoniae carried a class 1 integron containing bla(VIM-12), a novel bla(VIM)-type gene, flanked by two copies of aacA7. bla(VIM-12) was clustered between bla(VIM-1) and bLa(VIM-2) and differed from bla(VIM-1) by 18 nucleotides that were all located at the 3' end and matched the corresponding nucleotides in bla(VIM-2). The bla(VIM-12)-associated 59-base element was identical to that described in bla(VIM-2) alleles.

引用

页码：5153 / 5156

页数：4

共 23 条

[1] ARLET G, 1991, FEMS MICROBIOL LETT, V82, P19
[2] On functional and structural heterogeneity of VIM-type metallo-β-lactamases
Docquier, JD
Lamotte-Brasseur, J
Galleni, M
Amicosante, G
Frère, JM
Rossolini, GM
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 51 (02) : 257 - 266
[3] Standard numbering scheme for class B β-lactamases
Galleni, M
Lamotte-Brasseur, J
Rossolini, GM
Spencer, J
Dideberg, O
Frère, JM
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) : 660 - 663
[4] VIM-1 metallo-β-lactamase-producing Klebsiella pneumoniae strains in Greek hospitals
Giakkoupi, P
Xanthaki, A
Kanelopoulou, M
Vlahaki, A
Miriagou, V
Kontou, S
Papafraggas, E
Malamou-Lada, H
Tzouvelekis, LS
Legakis, NJ
Vatopoulos, AC
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (08) : 3893 - 3896
[5] Cloning and characterization of blaVIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate
Lauretti, L
Riccio, ML
Mazzariol, A
Cornaglia, G
Amicosante, G
Fontana, R
Rossolini, GM
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (07) : 1584 - 1590
[6] PCR MAPPING OF INTEGRONS REVEALS SEVERAL NOVEL COMBINATIONS OF RESISTANCE GENES
LEVESQUE, C
PICHE, L
LAROSE, C
ROY, PH
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) : 185 - 191
[7] Carbapenem-hydrolysing VIM-2 metallo-β-lactamase in Pseudomonas aeruginosa from Greece
Mavroidi, A
Tsakris, A
Tzelepi, E
Pournaras, S
Loukova, V
Tzouvelekis, LS
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 46 (06) : 1041 - 1043
[8] CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid
Miriagou, V
Tzouvelekis, LS
Villa, L
Lebessi, E
Vatopoulos, AC
Carattoli, A
Tzelepi, E
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (08) : 3172 - 3174
[9] Escherichia coli with a self-transferable, multiresistant plasmid coding for metallo-β-lactamase VIM-1
Miriagou, V
Tzelepi, E
Gianneli, D
Tzouvelekis, LS
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (01) : 395 - 397
[10] National Committee for Clinical Laboratory Standards, 1997, METH DIL ANT SUSC TE

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