Asymmetric synthesis of 1-alkoxy-2,2,2-trifluoroethanol derivatives

被引：15

作者：

Poras, H

Matsutani, H

Yaruva, J

Kusumoto, T

Hiyama, T

机构：

[1] Sagami Chem Res Ctr, Sagamihara, Kanagawa 2290012, Japan

[2] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6068501, Japan

来源：

CHEMISTRY LETTERS | 1998年 / 07期

关键词：

D O I：

10.1246/cl.1998.665

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of trifluoroacetaldehyde with an alcohol in the presence of a catalytic amount of (R)-BINOL-Ti(O-i-Pr)(2) gives optically active 1-alkoxy-2,2,2-trifluoroethanol with high ee.

引用

页码：665 / 666

页数：2

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