Pituitary function in the acute phase response in domestic farm animals: Cytokines, prostaglandins, and secretion of ACTH

被引：14

作者：

Abraham, EJ ^{[1
]}

Morris-Hardeman, JN ^{[1
]}

Swenson, LM ^{[1
]}

Knoppel, EL ^{[1
]}

Ramanathan, B ^{[1
]}

Wright, KJ ^{[1
]}

Grieger, DM ^{[1
]}

Minton, JE ^{[1
]}

机构：

[1] Kansas State Univ, Dept Anim Sci & Ind, Manhattan, KS 66506 USA

来源：

DOMESTIC ANIMAL ENDOCRINOLOGY | 1998年 / 15卷 / 05期

关键词：

D O I：

10.1016/S0739-7240(98)00020-4

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Contained in this report is a review of available data on pituitary cytokines in domestic species of agricultural importance. The concept is advanced that the pituitary gland is essential to appropriate generation of host defense mechanisms and thus should be considered among other tissues contributing to innate immunity. The functions of these intrapituitary cytokines, principally IL-6, are discussed in the context of potential regulation of the pituitary-adrenal axis (ACTH secretion) via intrapituitary PGE(2) generation during the acute-phase response to infectious/inflammatory stimuli. Data from other species are cited as appropriate for comparative purposes and elaboration of proposed mechanisms. However, the scope of the review is not intended to comprehensively cover the vast literature on proinflammatory cytokines and prostaglandins generated peripherally and centrally during host responses to inflammatory stimuli. (C) Elsevier Science Inc. 1998

引用

页码：389 / 396

页数：8

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