Long-term monitoring of gait in Parkinson's disease

被引：144

作者：

Moore, Steven T.

MacDougall, Hamish G.

Gracies, Jean-Michel

Cohen, Helen S.

Ondo, William G.

机构：

[1] Mt Sinai Sch Med, Dept Neurol, New York, NY 10029 USA

[2] Baylor Coll Med, Bobby R Alford Dept Otolaryngol Head & Neck Surg, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA

来源：

GAIT & POSTURE | 2007年 / 26卷 / 02期

关键词：

stride length; levodopa; parkinsonian; locomotion; accelerometer;

D O I：

10.1016/j.gaitpost.2006.09.011

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A new system for long-term monitoring of gait in Parkinson's disease (PD) has been developed and validated. The characteristics of every stride taken over 10-h epochs were acquired using a lightweight ankle-mounted sensor array that transmitted data wirelessly to a small pocket PC at a rate of 100 Hz. Stride was calculated from the vertical linear acceleration and pitch angular velocity of the leg with an accuracy of 5 cm. Results from PD patients (5) demonstrate the effectiveness of long-term monitoring of gait in a natural environment. The small, variable stride length characteristic of Parkinsonian gait, and fluctuations of efficacy associated with levodopa therapy, such as delayed onset, wearing off, and the 'off/on' effect, could reliably be detected from long-term changes in stride length. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：200 / 207

页数：8

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