Catalytic reductive N-alkylation of anilines. Application to the synthesis of N-aryl aminoacid precursors.

被引：26

作者：

Fache, F

Valot, F

Milenkovic, A

Lemaire, M

机构：

[1] UCBL,CPE,INST RECH CATALYSE,F-69622 VILLEURBANNE,FRANCE

[2] UNIV LYON 1,CPE,LAB CATALYSE & SYNTHESE ORGAN,F-69622 VILLEURBANNE,FRANCE

来源：

TETRAHEDRON | 1996年 / 52卷 / 29期

关键词：

D O I：

10.1016/0040-4020(96)00503-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Different anilines have been monoalkylated by reductive alkylation using ketones and alpha-ketoesters as alkylating agents with good isolated yields. This provided access to aminoacid derivatives. Diastereoselective experiments were also performed. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：9777 / 9784

页数：8

共 26 条

[1]

BADER R, 1995, Patent No. 5430188

[2]

Bader R, 1994, EP Patent, Patent No. 605363

[3] ALKYLATION OF AMINES USING TRIVALENT BISMUTH DERIVATIVES [J].