Carbamoylsilanes from the in situ metalation-silylation of a formamide

被引：15

作者：

Cunico, RF ^{[1
]}

机构：

[1] No Illinois Univ, Dept Chem & Biochem, De Kalb, IL 60115 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 08期

关键词：

metalation-silylation; carbamoylsilanes; carbamoyllithium; silyl group exchange;

D O I：

10.1016/S0040-4039(00)02275-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In situ treatment (-78 degreesC) of N-methoxymethyl-N-methylformamide and chlorotrimethylsilane with LDA affords synthetically useful yields of the carbamoylsilane. The latter undergoes silyl group exchange at 145 degreesC in the presence of a chlorosilane and CsF. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1423 / 1425

页数：3

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