Functional relevance of human ADH polymorphism

被引:49
作者
Eriksson, CJP
Fukunaga, T
Sarkola, T
Chen, WJ
Chen, CC
Ju, JM
Cheng, ATA
Yamamoto, H
Kohlenberg-Müller, K
Kimura, M
Murayama, M
Matsushita, S
Kashima, H
Higuchi, S
Carr, L
Viljoen, D
Brooke, L
Stewart, T
Foroud, T
Su, J
Li, TK
Whitfield, JB
机构
[1] Natl Publ Hlth Inst, Dept Mental Hlth & Alcohol Res, Helsinki 00101, Finland
[2] Mie Univ, Sch Med, Dept Forens Med & Sci, Tsu, Mie 514, Japan
[3] Natl Taiwan Univ, Coll Publ Hlth, Inst Epidemiol, Taipei 10764, Taiwan
[4] Taipei City Psychiat Ctr, Dept Adult Psychiat, Taipei, Taiwan
[5] Acad Sinica, Inst Biomed Sci, Div Epidemiol & Publ Hlth, Taipei 115, Taiwan
[6] Univ Appl Sci Fulda, Fulda, Germany
[7] Kurihama Natl Hosp, Div Clin Res, Natl Inst Alcoholism, Yokosuka, Kanagawa, Japan
[8] Akagi Kougen Hosp, Gunma, Japan
[9] Keio Univ, Sch Med, Dept Neuropsychiat, Tokyo, Japan
[10] Indiana Univ, Sch Med, Dept Med, Indianapolis, IN 46204 USA
[11] Fdn Alcohol Related Res, Cape Town, South Africa
[12] Royal Prince Alfred Hosp, Dept Clin Biochem, Camperdown, NSW 2050, Australia
关键词
ADH2; ADH3; polymorphism; alcohol drinking; flushing; birth defects;
D O I
10.1111/j.1530-0277.2001.tb02391.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were C. J. Peter Eriksson and Tatsushige Fukunaga. The presentations were (1) 4-Methylpyrazole as a tool in the investigation of the role of ADH in the actions of alcohol in humans, by Taisto Sarkola and C. J. Peter Eriksson; (2)ADH2 polymorphism and flushing in Asian populations, by Wei J. Chen, C. C. Chen, J. M. Ju, and Andrew T. A. Cheng; (3) Role of ADH3 genotypes in the acute effects of alcohol in a Finnish population, by Hidetaka Yamamoto, Kathrin Kohlenberg-Muller, and C. J. Peter Eriksson; (4) Clinical characteristics and disease course of alcoholics with different ADH2 genotypes, by Mitsuru Kimura, Masanobu Murayama, Sachio Matsushita, Haruo Kashima, and Susumu Higuchi; (5) ADH2 polymorphism, alcohol drinking, and birth defects, by Lucinda Carr, D. Viljoen, L. Brooke, T. Stewart, T. Foroud, J. Su, and Ting-Kai Li; and (6) ADH genotypes and alcohol use in Europeans, by John B. Whitfield.
引用
收藏
页码:157S / 163S
页数:7
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