共 43 条
A structural database for k-turn motifs in RNA
被引:64
作者:
Schroeder, Kersten T.
[1
]
McPhee, Scott A.
[1
]
Ouellet, Jonathan
[1
]
Lilley, David M. J.
[1
]
机构:
[1] Univ Dundee, Canc Res UK Nucle Acid Struct Res Grp, Dundee DD1 5EH, Scotland
来源:
基金:
英国惠康基金;
关键词:
RNA structure;
kink turn;
motif;
BOX C/D RNA;
PRERIBOSOMAL RNA;
MOLECULAR-BASIS;
BINDING MOTIF;
L7AE PROTEIN;
SITE;
LOOP;
RECOGNITION;
METHYLATION;
MUTATIONS;
D O I:
10.1261/rna.2207910
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The kink-turn (k-turn) is a common structural motif in RNA that introduces a tight kink into the helical axis. k-turns play an important architectural role in RNA structures and serve as binding sites for a number of proteins. We have created a database of known and postulated k-turn sequences and three-dimensional (3D) structures, available via the internet. This site provides (1) a database of sequence and structure, as a resource for the RNA community, and (2) a tool to enable the manipulation and comparison of 3D structures where known.
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页码:1463 / 1468
页数:6
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