A structural database for k-turn motifs in RNA

被引:64
作者
Schroeder, Kersten T. [1 ]
McPhee, Scott A. [1 ]
Ouellet, Jonathan [1 ]
Lilley, David M. J. [1 ]
机构
[1] Univ Dundee, Canc Res UK Nucle Acid Struct Res Grp, Dundee DD1 5EH, Scotland
基金
英国惠康基金;
关键词
RNA structure; kink turn; motif; BOX C/D RNA; PRERIBOSOMAL RNA; MOLECULAR-BASIS; BINDING MOTIF; L7AE PROTEIN; SITE; LOOP; RECOGNITION; METHYLATION; MUTATIONS;
D O I
10.1261/rna.2207910
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The kink-turn (k-turn) is a common structural motif in RNA that introduces a tight kink into the helical axis. k-turns play an important architectural role in RNA structures and serve as binding sites for a number of proteins. We have created a database of known and postulated k-turn sequences and three-dimensional (3D) structures, available via the internet. This site provides (1) a database of sequence and structure, as a resource for the RNA community, and (2) a tool to enable the manipulation and comparison of 3D structures where known.
引用
收藏
页码:1463 / 1468
页数:6
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