Click chemistry:: Copper clusters catalyse the cycloaddition of azides with terminal alkynes

被引：270

作者：

Pachón, LD ^{[1
]}

van Maarseveen, JH ^{[1
]}

Rothenberg, G ^{[1
]}

机构：

[1] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1018 WV Amsterdam, Netherlands

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2005年 / 347卷 / 06期

关键词：

azides; cycloaddition; kinetics; mechanism; nanoclusters; triple bonds;

D O I：

10.1002/adsc.200404383

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Air-stable copper nanoclusters are good catalysts in the Cu(I)-catalysed "click" cycloaddition of azides with terminal alkynes to give 1,4-disubstituted 1,2,3-triazoles. No additional base or reducing agent is required. The reaction kinetics using various copper catalyst types and the function of copper particles in this system are studied and discussed.

引用

页码：811 / 815

页数：5

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