Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates

被引：29

作者：

Von Seggern, CE

Moyer, SC

Cotter, RJ

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Pharmacol & Mol Sci, Baltimore, MD 21205 USA

[2] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA

来源：

ANALYTICAL CHEMISTRY | 2003年 / 75卷 / 13期

关键词：

D O I：

10.1021/ac0262006

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A 2.94-mum Er:YAG laser for IR atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used for the analysis of sialylated oligosaccharides. This approach provided the opportunity to utilize liquid matrixes and is effective in determining structural features-sequence, branching, and linkage-of intact, fully sialylated molecular species.

引用

页码：3212 / 3218

页数：7

共 27 条

[21] Achievements and challenges of sialic acid research [J].