Differences in effects on DNA gyrase activity between two glutamate racemases of Bacillus subtilis, the poly-γ-glutamate synthesis-linking Glr enzyme and the YrpC (MurI) isozyme

被引：31

作者：

Ashiuchi, M ^{[1
]}

Kuwana, E

Komatsu, K

Soda, K

Misono, H

机构：

[1] Kochi Univ, Dept Bioresources Sci, Nankoku, Kochi 7838502, Japan

[2] Kansai Univ, Dept Biotechnol, Suita, Osaka 5648680, Japan

来源：

FEMS MICROBIOLOGY LETTERS | 2003年 / 223卷 / 02期

关键词：

DNA gyrase; glutamate racemase; peptidoglycan; poly-gamma-glutamate; Bacillus subtilis;

D O I：

10.1016/S0378-1097(03)00381-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Bacillus subtilis possesses two isogenes encoding glutamate racemases, the poly-gamma-glutamate synthesis-linking Glr enzyme and the YrpC isozyme, and produces abundant amounts of the Glr enzyme. The YrpC isozyme, but not the Glr enzyme, was found to influence the activity of DNA gyrase. as did the Murl-type glutamate racemase of Escherichia coli, which is involved in peptidoglycan synthesis during cell division. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：221 / 225

页数：5

共 21 条

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