The Montreal Cognitive Assessment Short Cognitive Evaluation in a Large Stroke Trial

被引:70
作者
Cumming, Toby B. [1 ]
Bernhardt, Julie [1 ]
Linden, Thomas [2 ]
机构
[1] Florey Neurosci Inst, NSRI, Heidelberg, Vic 3084, Australia
[2] Gothenburg Univ, Ctr Brain Res & Rehabil, Gothenburg, Sweden
基金
英国医学研究理事会;
关键词
cerebrovascular disease; cognitive impairment; neuropsychology; vascular dementia; MINI-MENTAL-STATE; IMPAIRMENT;
D O I
10.1161/STROKEAHA.111.619486
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and Purpose-Cognitive function is often ignored in stroke research trials. The brief Montreal Cognitive Assessment (MoCA) may be sensitive to stroke-related cognitive deficits. Methods-We evaluated the feasibility of administering the MoCA at 3 months in a large stroke trial (A Very Early Rehabilitation Trial [AVERT]). Results-Data (blinded to intervention group) are presented for 294 patients with mean age of 70.6 years (SD, 12.8); 220 (75%) completed the MoCA, 54 (18%) had missing data, and 20 (7%) had died. Of those surviving to 3 months, the MoCA was completed by 87% with mild stroke, 79% with moderate stroke, and 67% with severe stroke on admission. Mean MoCA score was 21.1 (SD 7.5) out of 30; only 78 of 220 (35%) patients attained the "normal" cutoff (>= 26). Conclusions-The MoCA is a feasible global cognitive screening tool in stroke trials. Clinical Trial Registration-URL: www.anzctr.org.au/trial_view.aspx?ID=1266. Unique identifier: ACTRN12606000185561. (Stroke. 2011;42:2642-2644.)
引用
收藏
页码:2642 / 2644
页数:3
相关论文
共 9 条
[1]   Treatment of acute ischemic stroke: Does it impact neuropsychiatric outcome? [J].
Anderson, CA ;
Arciniegas, DB ;
Filley, CM .
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2005, 17 (04) :486-488
[2]  
BERNHARDT J, LANCET, P1081
[3]   MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[4]   National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards [J].
Hachinski, Vladimir ;
Iadecola, Costantino ;
Petersen, Ron C. ;
Breteler, Monique M. ;
Nyenhuis, David L. ;
Black, Sandra E. ;
Powers, William J. ;
DeCarli, Charles ;
Merino, Jose G. ;
Kalaria, Raj N. ;
Vinters, Harry V. ;
Holtzman, David M. ;
Rosenberg, Gary A. ;
Dichgans, Martin ;
Marler, John R. ;
Leblanc, Gabrielle G. .
STROKE, 2006, 37 (09) :2220-2241
[5]  
Jin Ya-Ping, 2006, Alzheimers Dement, V2, P171, DOI 10.1016/j.jalz.2006.03.006
[6]   The montreal cognitive assessment, MoCA:: A brief screening tool for mild cognitive impairment [J].
Nasreddine, ZS ;
Phillips, NA ;
Bédirian, V ;
Charbonneau, S ;
Whitehead, V ;
Collin, I ;
Cummings, JL ;
Chertkow, H .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2005, 53 (04) :695-699
[7]   Restrictions of the Mini-Mental State Examination in acute stroke [J].
Nys, GMS ;
van Zandvoort, MJE ;
de Kort, PLM ;
Jansen, BPW ;
Kappelle, LJ ;
de Haan, EHF .
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 2005, 20 (05) :623-629
[8]   Underestimation of Cognitive Impairment by Mini-Mental State Examination Versus the Montreal Cognitive Assessment in Patients With Transient Ischemic Attack and Stroke A Population-Based Study [J].
Pendlebury, Sarah T. ;
Cuthbertson, Fiona C. ;
Welch, Sarah J. V. ;
Mehta, Ziyah ;
Rothwell, Peter M. .
STROKE, 2010, 41 (06) :1290-1293
[9]   Mild cognitive impairment in symptomatic and asymptomatic cerebrovascular disease [J].
Popovic, Irena Martinic ;
Seric, Vesna ;
Demarin, Vida .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2007, 257 (1-2) :185-193