Different roles for androgens and estrogens in the susceptibility to autoimmune rheumatic diseases

被引：134

作者：

Cutolo, M

Wilder, RL

机构：

[1] Univ Genoa, Dept Internal Med, Div Rheumatol, I-16132 Genoa, Italy

[2] NIAMSD, Inflammatory Joint Dis Sect, NIH, Bethesda, MD 20892 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2000年 / 26卷 / 04期

关键词：

D O I：

10.1016/S0889-857X(05)70171-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Androgens and estrogens modulate susceptibility and progression to autoimmune rheumatic disease. At any concentration, androgens seem to be primarily suppressive on cellular and humoral immunity whereas at physiologic concentrations, estrogens seem to enhance humoral immunity and decrease cellular immunity.

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页码：825 / +

页数：16

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