Enantioselective intramolecular CH-insertions upon Cu-catalyzed decomposition of phenyliodonium ylides.

被引：27

作者：

Müller, P ^{[1
]}

Boléa, C ^{[1
]}

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

来源：

MOLECULES | 2001年 / 6卷 / 03期

关键词：

phenyliodonium ylides; CH insertion; Cu-catalysis; asymmetric induction;

D O I：

10.3390/60300258

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Cu-catalyzed intramolecular CH insertion of phenyliodonium ylide 5b has been investigated at 0 degrees C in the presence of several chiral ligands. Enantioselectivities vary in the range of 38-72 %, and are higher than those resulting from reaction of the diazo compound 5c at 65 degrees C. The results are consistent with a carbenoid mechanism for Cu-catalyzed decomposition of phenyliodonium ylides.

引用

页码：258 / 266

页数：9

共 33 条

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