Flow effect on lesion formation in RF cardiac catheter ablation

被引:34
作者
Cao, H
Vorperian, VR
Tungjitkusolmun, S
Tsai, JZ
Haemmerich, D
Bin Choy, Y
Webster, JG
机构
[1] Univ Wisconsin, Dept Biomed Engn, Madison, WI 53706 USA
[2] Univ Wisconsin, Dept Med, Madison, WI 53792 USA
[3] King Mongkuts Inst Technol, Fac Engn, Dept Elect, Bangkok 10520, Thailand
[4] King Mongkuts Inst Technol, Res Ctr Commun & Informat Technol, Bangkok 10520, Thailand
[5] Univ Wisconsin, Dept Elect & Comp Engn, Madison, WI 53706 USA
关键词
ablation; cardiac catheter ablation; convection film coefficient; lesion dimension; RF cardiac catheter ablation; temperature recording;
D O I
10.1109/10.915708
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study investigated the flow effect on the lesion formation during radio-frequency cardiac catheter ablation in temperature-controlled mode. The blood flow in heart chambers carries heat away from the endocardium by convection, This cooling effect requires more power from the ablation generator and causes a larger lesion. We set up a flow system to simulate the flow inside the heart chamber. We performed in vitro ablation on bovine myocardium with three different flow rates (0 L/min, 1 L/min and 3 L/min) and two target temperatures (60 degreesC and 80 degreesC). During ablation, we also recorded the temperatures inside the myocardium with a three-thermocouple temperature probe. The results show that lesion dimensions (maximum depth, maximum width and lesion volume) are larger in high flow rates (p < 0.01), Also, the temperature recordings show that the tissue temperature rises faster and reaches a higher temperature under higher flow rate.
引用
收藏
页码:425 / 433
页数:9
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