Effect of AOT-assisted multi-walled carbon nanotubes on antibacterial activity

被引:30
作者
Bai, Yu [1 ,2 ,5 ]
Park, Il Song [1 ,2 ]
Lee, Sook Jeong [3 ]
Wen, Pu Shan [4 ]
Bae, Tae Sung [1 ,2 ]
Lee, Min Ho [1 ,2 ]
机构
[1] Chonbuk Natl Univ, Brain Korea Project 21, Sch Dent, Dept Dent Biomat, Jeonju 561756, South Korea
[2] Chonbuk Natl Univ, Brain Korea Project 21, Inst Oral Biosci, Jeonju 561756, South Korea
[3] Univ Ulsan, Coll Med, Asan life Sci Inst, Dept Neurol,Neural Injury Res Lab, Seoul 138736, South Korea
[4] Chonbuk Natl Univ, Dept Adv Organ Mat Engn, Jeonju 561756, South Korea
[5] Inner Mongolia Univ Technol, Sch Mat Sci & Engn, Hohhot 010051, Peoples R China
基金
新加坡国家研究基金会;
关键词
MWCNTs; AOT surfactant; Dispersity; Antibacterial activity; Antibacterial agent; DISPERSION; CYTOTOXICITY; ADSORPTION;
D O I
10.1016/j.colsurfb.2011.09.001
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The dispersing power of surfactant-modified multiwalled carbon nanotubes (MWCNTs) and their effect on the antibacterial activity were examined. The MWCNTs were modified using a dioctyl sodium sulfosuccinate (AOT) surfactant. UV-vis spectroscopy and transmission electron microscopy (TEM) were used to characterize the dispersion of MWCNTs in the aqueous phase. Fourier transform infrared spectroscopy confirmed the results of UV-vis spectroscopy and TEM, indicating that the AOT molecules had been adsorbed successfully onto the MWCNT surface. The highly dispersed AOT-modified MWCNTs showed strong antibacterial activity to Streptococcus mu fans. The fluorescence images showed that the AOT-modified MWCNTs were capable of capturing bacteria and forming cell aggregates as well as killing them. The optical density growth curves and colony-forming units assays confirmed that the antibacterial activity of the AOT-modified MWCNTs was concentration-dependent and treatment time-dependent. This finding might be useful for applications of AOT-modified MWCNTs as an antibacterial agent to eliminate pathogens from a biocontaminated water phase. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:101 / 107
页数:7
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