Vascular calcification in patients with chronic kidney disease

被引：24

作者：

Dellegrottaglie, S

Sanz, J

Rajagopalan, S

机构：

[1] Mt Sinai Med Ctr, Zena & Michael A Wiener Cardiovasc Inst, New York, NY 10029 USA

[2] Mt Sinai Med Ctr, Marie Josee & Henry R Kravis Ctr Cardiovasc Hlth, New York, NY 10029 USA

来源：

BLOOD PURIFICATION | 2006年 / 24卷 / 01期

关键词：

vascular calcification; chronic kidney disease; end-stage renal disease; cardiovascular disease; atherosclerosis;

D O I：

10.1159/000089438

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chronic kidney disease (CKD) represents an extremely common condition, and cardiovascular diseases are frequently reported in this patient population. Traditional risk factors are not accurate prognostic predictors in CKD patients, and new potential markers to predict the cardiovascular involvement in uremic patients need to be identified. Vascular calcification (VC) represents a hallmark of the atherosclerotic process in CKD. This review summarizes the processes responsible for VC (particularly focusing on the mechanisms operative in the presence of renal dysfunction), discusses the utility of computer tomography modalities in the detection of VC in patients with CKD, and reports the potential role of VC as pathophysiological link between kidney disease and cardiovascular events. Copyright (C) 2006 S. Karger AG, Basel.

引用

收藏

页码：56 / 62

页数：7

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