Cytokine signaling to the cell cycle

被引：14

作者：

Quelle, Frederick W. ^{[1
]}

机构：

[1] Univ Iowa, Grad Program Immunol, Dept Pharmacol, Iowa City, IA 52242 USA

来源：

IMMUNOLOGIC RESEARCH | 2007年 / 39卷 / 1-3期

关键词：

cytokine; cytokine receptor; signal transduction; cell cycle;

D O I：

10.1007/s12026-007-0080-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The proliferation of many myeloid and lymphoid cell populations is directly controlled by cytokine growth factors acting through a related family of cytokine receptors. This regulation implies that the signaling pathways activated by cytokine receptors must communicate with mechanisms that control mammalian cell cycle progression. Evidence for how these signaling pathways promote hematopoietic cell proliferation is considered along with their likely targets among the cell cycle regulators.

引用

页码：173 / 184

页数：12

共 105 条

[31] Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells [J].

Henry, MK ;

Nimbalkar, D ;

Hohl, RJ ;

Quelle, FW .

EXPERIMENTAL CELL RESEARCH, 2004, 299 (01) :257-266

[32] DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway [J].

Henry, MK ;

Lynch, JT ;

Eapen, AK ;

Quelle, FW .

BLOOD, 2001, 98 (03) :834-841

[33]

HENRY MK, 2001, KEYSTONE S MOL BASIS

[34] Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation [J].

Hoelbl, Andrea ;

Kovacic, Boris ;

Kerenyi, Marc A. ;

Simma, Olivia ;

Warsch, Wolfgang ;

Cui, Yongzhi ;

Beug, Hartmut ;

Hennighausen, Lothar ;

Moriggl, Richard ;

Sexl, Veronika .

BLOOD, 2006, 107 (12) :4898-4906

[35] A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera [J].

James, C ;

Ugo, V ;

Le Couédic, JP ;

Staerk, J ;

Delhommeau, F ;

Lacout, C ;

Garçon, L ;

Raslova, H ;

Berger, R ;

Bennaceur-Griscelli, A ;

Villeval, JL ;

Constantinescu, SN ;

Casadevall, N ;

Vainchenker, W .

NATURE, 2005, 434 (7037) :1144-1148

[36] Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a [J].

Janzen, Viktor ;

Forkert, Randolf ;

Fleming, Heather E. ;

Saito, Yoriko ;

Waring, Michael T. ;

Dombkowski, David M. ;

Cheng, Tao ;

DePinho, Ronald A. ;

Sharpless, Norman E. ;

Scadden, David T. .

NATURE, 2006, 443 (7110) :421-426

[37] Analysis of CAK activities from human cells [J].

Kaldis, P ;

Solomon, MJ .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 2000, 267 (13) :4213-4221

[38] The cdk-activating kinase (CAK): from yeast to mammals [J].

Kaldis, P .

CELLULAR AND MOLECULAR LIFE SCIENCES, 1999, 55 (02) :284-296

[39] Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells [J].

Kaplan, MH ;

Schindler, U ;

Smiley, ST ;

Grusby, MJ .

IMMUNITY, 1996, 4 (03) :313-319

[40] Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice [J].

Kaplan, MH ;

Sun, YL ;

Hoey, T ;

Grusby, MJ .

NATURE, 1996, 382 (6587) :174-177

← 1 2 3 4 5 6 7 8 9 10 →