Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases

被引：917

作者：

Merzendorfer, H ^{[1
]}

Zimoch, L ^{[1
]}

机构：

[1] Univ Osnabruck, Dept Biol Chem, D-49069 Osnabruck, Germany

来源：

JOURNAL OF EXPERIMENTAL BIOLOGY | 2003年 / 206卷 / 24期

关键词：

chitin; chitin synthesis; chitin synthase; chitinase; cuticle; peritrophic matrix; insect;

D O I：

10.1242/jeb.00709

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Chitin is one of the most important biopolymers in nature. It is mainly produced by fungi, arthropods and nematodes. In insects, it functions as scaffold material, supporting the cuticles of the epidermis and trachea as well as the peritrophic matrices lining the gut epithelium. Insect growth and morphogenesis are strictly dependent on the capability to remodel chitin-containing structures. For this purpose, insects repeatedly produce chitin synthases and chitinolytic enzymes in different tissues. Coordination of chitin synthesis and its degradation requires strict control of the participating enzymes during development. In this review, we will summarize recent advances in understanding chitin synthesis and its degradation in insects.

引用

页码：4393 / 4412

页数：20

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