HIV superinfection

被引：196

作者：

Smith, DM

Richman, DD

Little, SJ

机构：

[1] Univ Calif San Diego, La Jolla, CA 92093 USA

[2] Vet Affairs San Diego Healthcare Syst, San Diego, CA USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2005年 / 192卷 / 03期

关键词：

D O I：

10.1086/431682

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications concerning our understanding of worldwide HIV diversity, individual immunity and disease progression, and vaccine development. Here, we review the current understanding of HIV superinfection.

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页码：438 / 444

页数：7

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