Biofilms and catheter-associated urinary tract infections

被引：225

作者：

Saint, S ^{[1
]}

Chenoweth, CE

机构：

[1] Ann Arbor VA Med Ctr, Ann Arbor, MI 48105 USA

[2] Univ Michigan Hlth Syst, Dept Med, Ann Arbor, MI 48109 USA

[3] Univ Michigan Hlth Syst, Patient Safety Enhancement Program, Ann Arbor, MI 48109 USA

[4] Univ Michigan Hlth Syst, Div Infect Dis Infect Control & Epidemiol, Ann Arbor, MI 48109 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2003年 / 17卷 / 02期

关键词：

D O I：

10.1016/S0891-5520(03)00011-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Catheter-related urinary tract infections (UTI) are common, costly, and morbid and affect several different populations including hospitalized patients, residents of extended care facilities, and persons with injured spinal cords. Biofilm, a collection of microbial organisms on a surface surrounded by an extracellular matrix made up of primarily polysaccharide materials, readily develops on both the internal and external surface of the urinary catheter. Biofilm presence has important implications for antimicrobial resistance and for the diagnosis, prevention, and treatment of catheter-related UTI. In addition to discussing the pathogenesis of catheter-related UTI, the authors provide an overview of the risk factors, microbiology, clinical manifestations, management, and prevention of catheter-related infection.

引用

页码：411 / +

页数：23

共 149 条

[91] An economic model to assess the cost and benefits of the routine use of silver alloy coated urinary catheters to reduce the risk of urinary tract infections in catheterized patients [J].