Use of 99mTc (V) DMSA scintigraphy in the detection and localization of intestinal inflammation:: Comparison of findings at colonoscopy and biopsy

被引：21

作者：

Lee, BF

Chiu, NT

Wu, DC

Tsai, KB

Liu, GC

Yu, HS

Wang, ST

机构：

[1] Natl Cheng Kung Univ Hosp, Dept Nucl Med, Tainan 704, Taiwan

[2] Natl Cheng Kung Univ Hosp, Inst Publ Hlth, Tainan 704, Taiwan

[3] Kaohsiung Med Univ Hosp, Inst Med, Kaohsiung, Taiwan

[4] Kaohsiung Med Univ Hosp, Dept Internal Med, Kaohsiung, Taiwan

[5] Kaohsiung Med Univ Hosp, Dept Radiol, Kaohsiung, Taiwan

[6] Kaohsiung Med Univ Hosp, Dept Pathol, Kaohsiung, Taiwan

来源：

RADIOLOGY | 2001年 / 220卷 / 02期

关键词：

colonoscopy; enteritis; inflammation; radionuclide studies; intestines; biopsy;

D O I：

10.1148/radiology.220.2.r01au30381

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

PURPOSE: To evaluate the potential use of technetium 99m (Tc-99m) (V) dimercaptosuccinic acid (DMSA) scintigraphy in the detection and localization of intestinal inflammation. MATERIALS AND METHODS: In a prospective study, 62 patients who were suspected of having intestinal inflammation and SO control subjects were enrolled. All patients underwent Tc-99m (V) DMSA scintigraphy and colonoscopy with biopsy within 1 week. Tc-99m (V) DMSA scintigrams were interpreted blindly with respect to clinical information, and radiotracer uptake in the bowel segments was graded. The findings were then compared with the results of the colonoscopy and colonoscopic biopsy. RESULTS: In the detection of intestinal inflammation, findings at Tc-99m (V) DMSA scintigraphy were as follows: true-positive in 55, false-positive in two, true-negative in 32, and false-negative in three. Overall sensitivity was 95%; overall specificity, 94%; and overall accuracy, 95%. CONCLUSION: Our results show that Tc-99m (V) DMSA scintigraphy is a useful noninvasive diagnostic test for the detection and localization of intestinal inflammation.

引用

页码：381 / 385

页数：5

共 34 条

[31] Evaluation of (99)mTc-citrate, Ga-67-citrate and Tc-99m(V) dimercaptosuccinic acid for the scintigraphic visualization of acute appendicitis [J].