Synthesis of isoquinolines and naphthyridines by electrophilic ring closure of iminoalkynes

被引：138

作者：

Huang, QH ^{[1
]}

Hunter, JA ^{[1
]}

Larock, RC ^{[1
]}

机构：

[1] Iowa State Univ Sci & Technol, Dept Chem, Ames, IA 50011 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 19期

关键词：

D O I：

10.1021/ol010136h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Substituted isoquinolines and naphthyridines have been prepared in good to excellent yields by the reaction of iminoalkynes with a variety of electrophiles under mild reaction conditions.

引用

页码：2973 / 2976

页数：4

共 21 条

[1] ANDERSON CD, 1980, J CHEM SOC P1, P1331
[2] A new approach to 2,3-disubstituted benzo[b]furans from o-alkynylphenols via 5-endo-dig-iodocyclisation/palladium-catalysed reactions
Arcadi, A
Cacchi, S
Fabrizi, G
Marinelli, F
Moro, L
[J]. SYNLETT, 1999, (09) : 1432 - 1434
[3] A NEW VERSATILE SYNTHESIS OF ISOQUINOLINES BY CONDENSATION OF IMINOPHOSPHORANES WITH ORTHO-PHTHALALDEHYDE
AUBERT, T
FARNIER, M
HANQUET, B
GUILARD, R
[J]. SYNTHETIC COMMUNICATIONS, 1987, 17 (15) : 1831 - 1837
[4] BOBBITT JM, 1987, HETEROCYCLES, V25, P601
[5] A NEW PREPARATION OF DIFUNCTIONALIZED ENAMINES FROM THIOAMIDES USING SILVER(I) CARBONATE
BRILLON, D
SAUVE, G
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (07) : 2246 - 2249
[6] First synthesis of the antimalarial naphthylisoquinoline alkaloid dioncophylline C, and its unnatural anti-HIV dimer, jozimine C
Bringmann, G
Holenz, J
Weirich, R
Rübenacker, M
Funke, C
Boyd, MR
Gulakowski, RJ
François, G
[J]. TETRAHEDRON, 1998, 54 (3-4) : 497 - 512
[7] BROSSI A, 1988, HETEROCYCLES, V12, P2905
[8] Antidesmone, a novel type isoquinoline alkaloid from Antidesma membranaceum (Euphorbiaceae)
Buske, A
Busemann, S
Mühlbacher, J
Schmidt, J
Porzel, A
Bringmann, G
Adam, G
[J]. TETRAHEDRON, 1999, 55 (04) : 1079 - 1086
[9] Synthesis of isoquinolines and pyridines via palladium-catalysed iminoannulation of allenes
Diederen, JJH
Sinkeldam, RW
Frühauf, HW
Hiemstra, H
Vrieze, K
[J]. TETRAHEDRON LETTERS, 1999, 40 (22) : 4255 - 4258
[10] REACTION OF BENZOCYCLOBUTENOXIDES WITH NITRILES - SYNTHESIS OF HYPECUMINE AND OTHER 3-SUBSTITUTED ISOQUINOLINES
FITZGERALD, JJ
MICHAEL, FE
OLOFSON, RA
[J]. TETRAHEDRON LETTERS, 1994, 35 (49) : 9191 - 9194

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