Variables associated with familial suicide attempts in a sample of suicide attempters

被引:25
作者
Baca-Garcia, Enrique
Perez-Rodriguez, M. Mercedes
Saiz-Gonzalez, Dolores
Basurte-Villamor, Ignacio
Saiz-Ruiz, Jeronimo
Leiva-Murillo, Jose M.
de Prado-Cumplido, Mario
Santiago-Mozos, Ricardo
Artes-Rodriguez, Antonio
de Leon, Jose
机构
[1] Eastern State Hosp, Mental Hlth Res Ctr, Lexington, KY 40508 USA
[2] Univ Autonoma Madrid, Fdn Jimenez Diaz Univ Hosp, Dept Psychiat, Madrid 28040, Spain
[3] Hosp Ramon & Cajal, Dept Psychiat, Madrid 28034, Spain
[4] Univ Alcala, Dept Psychiat, Madrid, Spain
[5] Univ Carlos III Madrid, Telecommun Engn Fac, Dept Signal Theory, Madrid 28911, Spain
关键词
alcohol drinking; alcohol-related disorders; attempted suicide; genetics; suicide;
D O I
10.1016/j.pnpbp.2007.05.019
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Attempted suicide appears to be a familial behavior. This study aims to determine the variables associated with family history of attempted suicide in a large sample of suicide attempters. The sample included 539 suicide attempters 18 years or older recruited in an emergency room. The two dichotomous dependent variables were family history of suicide attempt (10%, 51/539) and. of completed suicide (4%, 23/539). Independent variables were 10 1 clinical variables studied with two data mining techniques: Random Forest and For-ward Selection. A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide (sensitivity, specificity, 98.7%; and accuracy, 96.6%). This is the first study that uses a powerful new statistical methodology, data mining, in the field of familial suicidal behaviors and suggests that it may be important to study familial variables associated with alcohol use to better understand the familiality of suicide attempts. (C) 2007 Elsevier Inc. All fights reserved.
引用
收藏
页码:1312 / 1316
页数:5
相关论文
共 38 条
[11]   Behavioural and emotional problems in children of alcoholic mothers and fathers [J].
Christensen, HB ;
Bilenberg, N .
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2000, 9 (03) :219-226
[12]   Familial suicide behaviour: association with probands suicide attempt characteristics and 5-HTTLPR polymorphism [J].
Correa, H ;
Campi-Azevedo, AC ;
De Marco, L ;
Boson, W ;
Viana, MM ;
Guimaraes, MM ;
Costa, E ;
Miranda, DM ;
Romano-Silva, MA .
ACTA PSYCHIATRICA SCANDINAVICA, 2004, 110 (06) :459-464
[13]   Suicidal behavior: Relationship between phenotype and serotonergic genotype [J].
Courtet, P ;
Jollant, F ;
Castelnau, D ;
Buresi, C ;
Malafosse, A .
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS, 2005, 133C (01) :25-33
[14]   Dimensions of suicidal behavior according to patient reports [J].
Diaz, FJ ;
Baca-Garcia, E ;
Diaz-Sastre, C ;
Resa, EG ;
Blasco, H ;
Conesa, DB ;
Saiz-Ruiz, J ;
de Leon, J .
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2003, 253 (04) :197-202
[15]   SUICIDE AND FAMILY LOADING FOR AFFECTIVE-DISORDERS [J].
EGELAND, JA ;
SUSSEX, JN .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1985, 254 (07) :915-918
[16]   Data mining issues and opportunities for building nursing knowledge [J].
Goodwin, L ;
VanDyne, M ;
Lin, S ;
Talbert, S .
JOURNAL OF BIOMEDICAL INFORMATICS, 2003, 36 (4-5) :379-388
[17]   Serotonin transporter gene polymorphisms, alcoholism, and suicidal behavior [J].
Gorwood, P ;
Batel, P ;
Adès, J ;
Hamon, M ;
Boni, C .
BIOLOGICAL PSYCHIATRY, 2000, 48 (04) :259-264
[18]  
Guyon I, 2003, J MACH LEARN RES, P1157, DOI [10.1016/j.aca.2011.07.027, DOI 10.1016/J.ACA.2011.07.027]
[19]   Mining medical data [J].
Hand, DJ .
STATISTICAL METHODS IN MEDICAL RESEARCH, 2000, 9 (04) :305-307
[20]   Impulsivity and aggression as predictors of suicide attempts in alcoholics [J].
Koller, G ;
Preuss, UW ;
Bottlender, M ;
Wenzel, K ;
Soyka, M .
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2002, 252 (04) :155-160