Severe infection with Clostridium difficile PCR ribotype 027 acquired in Melbourne, Australia

被引:41
作者
Richards, Michael [1 ]
Knox, James [2 ,3 ]
Elliott, Briony [4 ]
Mackin, Kate [5 ]
Lyras, Dena [5 ]
Waring, Lynette J. [3 ]
Riley, Thomas V. [4 ,6 ]
机构
[1] Royal Melbourne Hosp, Victorian Infect Dis Serv, Melbourne, Vic, Australia
[2] Monash Med Ctr, Dept Infect Dis, Melbourne, Vic, Australia
[3] Melbourne Pathol, Melbourne, Vic, Australia
[4] Univ Western Australia, Perth, WA 6009, Australia
[5] Monash Univ, Dept Microbiol, Melbourne, Vic 3004, Australia
[6] PathWest Lab Med, Perth, WA, Australia
关键词
EPIDEMIC; DIARRHEA; COLITIS; METRONIDAZOLE; VANCOMYCIN; DIAGNOSIS; AMERICA; DISEASE; STRAIN;
D O I
10.5694/j.1326-5377.2011.tb03012.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report the first recognised case of infection with Clostridium difficile PCR ribotype 027 acquired in Australia. This pathogen has caused significant morbidity and mortality in widespread hospital-based outbreaks in the northern hemisphere. Clinicians need to be aware of the clinical picture, limitations of diagnostic tests, availability of further testing for epidemic strains, new therapeutic approaches, and in-hospital control strategies for this infection. (MJA 2011; 194: 369-371)
引用
收藏
页码:369 / 371
页数:3
相关论文
共 19 条
[1]  
AKSENOKA K, 2009, ACTA CHIRURG LATVIEN, V9, P56
[2]   Adjunctive intracolonic vancomycin for severe Clostridium difficile colitis:: Case series and review of the literature [J].
Apisarnthanarak, A ;
Razavi, B ;
Mundy, LM .
CLINICAL INFECTIOUS DISEASES, 2002, 35 (06) :690-696
[3]   FECAL METRONIDAZOLE CONCENTRATIONS DURING ORAL AND INTRAVENOUS THERAPY FOR ANTIBIOTIC ASSOCIATED COLITIS DUE TO CLOSTRIDIUM-DIFFICILE [J].
BOLTON, RP ;
CULSHAW, MA .
GUT, 1986, 27 (10) :1169-1172
[4]  
CHENG AC, 2011, MED J AUST, V194
[5]   Clostridium difficile PCR ribotype 027: assessing the risks of further worldwide spread [J].
Clements, Archie C. A. ;
Magalhaes, Ricardo J. Soares ;
Tatem, Andrew J. ;
Paterson, David L. ;
Riley, Thomas V. .
LANCET INFECTIOUS DISEASES, 2010, 10 (06) :395-404
[6]   Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) [J].
Cohen, Stuart H. ;
Gerding, Dale N. ;
Johnson, Stuart ;
Kelly, Ciaran P. ;
Loo, Vivian G. ;
McDonald, L. Clifford ;
Pepin, Jacques ;
Wilcox, Mark H. .
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2010, 31 (05) :431-455
[7]   Impact of emergency colectomy on survival of patients with fulminant Clostridium difficile colitis during an epidemic caused by a hypervirulent strain [J].
Lamontagne, Francois ;
Labbe, Annie-Claude ;
Haeck, Olivier ;
Lesur, Olivier ;
Lalancette, Mathieu ;
Patino, Carlos ;
Leblanc, Martine ;
Laverdiere, Michel ;
Pepin, Jacques .
ANNALS OF SURGERY, 2007, 245 (02) :267-272
[8]   A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality [J].
Loo, VG ;
Poirier, L ;
Miller, MA ;
Oughton, M ;
Libman, MD ;
Michaud, S ;
Bourgault, AM ;
Nguyen, T ;
Frenette, C ;
Kelly, M ;
Vibien, A ;
Brassard, P ;
Fenn, S ;
Dewar, K ;
Hudson, TJ ;
Horn, R ;
René, P ;
Monczak, Y ;
Dascal, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (23) :2442-2449
[9]   An epidemic, toxin gene-variant strain of Clostridium difficile [J].
McDonald, LC ;
Killgore, GE ;
Thompson, A ;
Owens, RC ;
Kazakova, SV ;
Sambol, SP ;
Johnson, S ;
Gerding, DN .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (23) :2433-2441
[10]   Clinical management of Clostridium difficile -: Associated disease [J].
Miller, Mark A. .
CLINICAL INFECTIOUS DISEASES, 2007, 45 :S122-S128